Cognitive, focus & mood
P21 (P021)
An experimental peptide derived from ciliary neurotrophic factor (CNTF), studied in animal models of cognitive decline.
How it works
Derived from ciliary neurotrophic factor (CNTF). In mice it increased the birth of new neurons in the hippocampus and reduced tau damage.
What it is used for
Alzheimer’s disease and memory.
What the evidence says
Mouse studies only.
Side effects and cautions
Its safety is unknown.
Half-life
Not established in people
Makes sense for
- Cognitive research only
Does not make sense for
- Anyone who needs proven results
Boost the effect
- Aerobic exercise: raises BDNF and supports brain plasticity
- Omega-3 (DHA) from fish: a building block of brain cell membranes
- Regular, sufficient sleep: when the brain consolidates memory