Longevity & cellular health

NAD+

A coenzyme present in every cell and essential for energy production. Its levels drop with age.

Not a peptide. Included because it is part of the catalog and the dosage sheet.

How it works

A coenzyme every cell needs to make energy, and the fuel for enzymes that repair DNA (sirtuins and PARPs).

What it is used for

Anti-aging, fatigue and recovery from addiction, as offered in clinics.

What the evidence says

Small studies only. Clear health benefits have not been shown, and injected NAD+ is broken down quickly.

Side effects and cautions

Flushing, nausea, chest tightness and cramps, especially if given fast. Injections under the skin can sting.

Half-life

Minutes: it is quickly broken down in the body

Makes sense for

  • Adults with fatigue looking to support energy metabolism

Does not make sense for

  • Active cancer
  • People sensitive to flushing or nausea

Boost the effect

  • Exercise: raises NAD+ naturally
  • TMG (trimethylglycine): replaces methyl groups the body uses up when clearing extra NAD+ (community practice)