Recovery, repair & inflammation
BPC-157
A synthetic peptide based on a protein found in gastric juice, widely studied in animals for tendon, muscle and gut repair. Human data is very limited.
How it works
In animals it boosts the growth of new blood vessels, the activity of tendon cells and nitric-oxide signaling, all of which help tissue repair.
What it is used for
Healing of tendons, ligaments, muscle and the gut (ulcers, inflammatory bowel disease).
What the evidence says
More than a hundred animal studies, mostly from one research group. Human data is limited to a few small pilot studies, for example on knee pain.
Side effects and cautions
There are no proper human safety trials. Because it grows blood vessels, there is a theoretical concern about tumors. It is banned in sport (WADA), and product quality varies.
Half-life
Under 30 minutes in animals; not established in people
Makes sense for
- Adults with tendon, ligament, muscle or gut injuries who accept animal-only evidence
Does not make sense for
- Active cancer or a history of cancer
- Competitive athletes (banned in sport)
Boost the effect
- Collagen or gelatin (10–15 g) with 50 mg of vitamin C, 30–60 minutes before rehab exercise: supports collagen in tendons and ligaments
- Enough protein: tissue repair needs amino acids
- Gentle, progressive loading of the injured area: guides how the new tissue forms